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Nominee
|
| |
Director
Since |
| |
Principal Occupation or Experience
|
| |
Committees
|
|
Gregory J. Divis | | |
2019
|
| | Chief Executive Office of the Company. | | | | |
Dr. Eric J. Ende | | |
2018
|
| | President at Ende BioMedical Consulting Group; Director at Matinas BioPharma, Inc. | | |
(2)(3)(4*)
|
|
Geoffrey M. Glass | | |
2018
|
| | President at Clear Sciences, LLC; former Chief Executive Officer and Director at Sancilio Pharmaceuticals | | |
(1)(2)(3)(4)
|
|
Dr. Mark A. McCamish
|
| |
2019
|
| | President and Chief Executive Officer of Forty Seven, Inc. | | |
(2)
|
|
Linda S. Palczuk | | |
2018
|
| | Chief Operating Officer and Director of Envara Health, Inc. | | |
(3*)(4)
|
|
Peter Thornton | | |
2017
|
| | Chief Financial Officer at Technopath Clinical Diagnostics | | |
(2*)(3)(4)
|
|
Name
|
| |
Age
|
| |
Position
|
|
Gregory J. Divis | | |
54
|
| | Chief Executive Officer and Director | |
Thomas S. McHugh | | |
55
|
| | Chief Financial Officer | |
Jordan S. Dubow, M.D. | | |
42
|
| | Chief Medical Officer | |
Geoffrey M. Glass | | |
46
|
| | Chairman of the Board of Directors | |
Eric J. Ende, M.D. | | |
51
|
| | Director | |
Mark A. McCamish, M.D., Ph.D. | | |
68
|
| | Director | |
Linda S. Palczuk | | |
58
|
| | Director | |
Peter Thornton | | |
55
|
| | Director | |
Name
|
| |
Fees Earned or
Paid in Cash ($)(1) |
| |
Option
Awards ($)(2)(3) |
| |
Stock
Awards ($)(2)(4) |
| |
Total
Compensation ($) |
| ||||||||||||
Geoffrey M. Glass(5)
|
| | | $ | 305,024(6) | | | | | | 67,800 | | | | | | — | | | | | $ | 372,824 | | |
Dr. Eric J. Ende(7)
|
| | | $ | 64,719 | | | | | | 74,500 | | | | | | 42,129 | | | | | $ | 181,348 | | |
Dr. Mark A. McCamish(8)
|
| | | $ | — | | | | | | — | | | | | | — | | | | | $ | — | | |
Linda S. Palczuk(9)
|
| | | $ | 67,453 | | | | | | 67,800 | | | | | | — | | | | | $ | 135,253 | | |
Peter Thornton(10)
|
| | | $ | 73,338 | | | | | | 67,800 | | | | | | — | | | | | $ | 141,138 | | |
Kevin Kotler(11)
|
| | | $ | 54,405 | | | | | | 67,800 | | | | | | 42,129 | | | | | $ | 164,334 | | |
Craig Stapleton
|
| | | $ | 17,113 | | | | | | — | | | | | | — | | | | | $ | 17,113 | | |
Name and Address of Beneficial Owners(1)
|
| |
Amount of
Beneficial Ownership(2) |
| |
Percentage of
Class(2) |
| ||||||
>5% Shareholders: | | | | | | | | | | | | | |
RTW Investments, L.P.(3)
415 West 15th Street, Floor 9 New York, NY 10011 |
| | | | 4,616,570 | | | | | | 9.95% | | |
Vivo Capital LLC(4)
192 Lytton Avenue Palo Alto, CA 94301 |
| | | | 3,526,093 | | | | | | 7.60% | | |
Avoro Capital Advisors LLC(5)
110 Greene Street, Suite 800, New York, NY 10012 |
| | | | 3,895,655 | | | | | | 8.39% | | |
Directors, Director Nominees and Named Executive Officers: | | | | | | | | | | | | | |
Gregory J. Divis(6)
|
| | | | 186,100 | | | | | | * | | |
Thomas S. McHugh
|
| | | | — | | | | | | * | | |
Dr. Jordan S. Dubow(7)
|
| | | | 85,000 | | | | | | * | | |
Phillandas T. Thompson
|
| | | | 113,671 | | | | | | * | | |
Sandra Hatten
|
| | | | 59,165 | | | | | | * | | |
Michael F. Kanan
|
| | | | 50,538 | | | | | | * | | |
Geoffrey M. Glass
|
| | | | 47,900 | | | | | | * | | |
Dr. Eric J. Ende
|
| | | | 47,900 | | | | | | * | | |
Dr. Mark A. McCamish
|
| | | | — | | | | | | * | | |
Linda S. Palczuk
|
| | | | 35,400 | | | | | | * | | |
Peter Thornton
|
| | | | 33,055 | | | | | | * | | |
All directors and executive officers as a group (11 persons)(8)
|
| | | | 658,729 | | | | | | 1.41% | | |
Name
|
| |
Position
|
|
Gregory J. Divis | | | Chief Executive Officer | |
Thomas S. McHugh | | | Senior Vice President and Chief Financial Officer | |
Michael F. Kanan | | | Former Chief Financial Officer | |
Phillandas T. Thompson | | | Senior Vice President, General Counsel and Corporate Secretary | |
Jordan S. Dubow, M.D. | | | Chief Medical Officer | |
|
2019 Peer Group
|
| |||
|
Aeglea BioTherapeutics, Inc.
|
| |
Iterum Therapeutics plc
|
|
|
Aldeyra Therapeutics, Inc.
|
| |
Marinus Pharmaceuticals, Inc.
|
|
|
Allena Pharmaceuticals, Inc.
|
| |
Millendo Theraeputics, Inc.
|
|
|
Aridis Pharmaceuticals, Inc.
|
| |
Otonomy, Inc.
|
|
|
Catalyst Biosciences, Inc.
|
| |
Savara Inc.
|
|
|
Chiasma, Inc.
|
| |
Sesen Bio
|
|
|
Chimerix
|
| |
Spero Therapeutics, Inc.
|
|
|
CymaBay Therapeutics, Inc.
|
| |
Syndax Pharmaceuticals, Inc.
|
|
|
Entasis Therapeutics Holdings Inc.
|
| |
Zynerba Pharmaceuticals, Inc.
|
|
|
GlycoMimetics, Inc.
|
| | | |
Name
|
| |
2018 Base
Salary ($) |
| |
2019 Base
Salary ($) |
| |
Increase
(%) |
| |||||||||
Gregory J. Divis
|
| | | | 425,000 | | | | | | 433,500(1) | | | | | | 2% | | |
Thomas S. McHugh(2)
|
| | | | — | | | | | | 385,000 | | | | | | — | | |
Sandra Hatten
|
| | | | 314,445 | | | | | | 323,092 | | | | | | 2.7% | | |
Michael F. Kanan
|
| | | | 386,100 | | | | | | 396,718 | | | | | | 2.7% | | |
Phillandas Thompson
|
| | | | 365,968 | | | | | | 383,400 | | | | | | 4.5% | | |
Jordan S. Dubow, M.D.(3)
|
| | | | — | | | | | | 435,000 | | | | | | — | | |
Name
|
| |
2019 Target Bonus
(as a % of Base Salary) |
| |
2019
Target Bonus ($) |
| ||||||
Gregory J. Divis(1)
|
| | | | 50% | | | | | | 265,312 | | |
Thomas S. McHugh(2)
|
| | | | — | | | | | | — | | |
Michael F. Kanan
|
| | | | 40% | | | | | | 158,687 | | |
Phillandas Thompson
|
| | | | 40% | | | | | | 153,360 | | |
Jordan S. Dubow, M.D.
|
| | | | 45% | | | | | | 195,750 | | |
Sandra Hatten
|
| | | | 40% | | | | | | 129,237 | | |
Name
|
| |
Stock
Options |
| |
Restricted
Shares |
| ||||||
Gregory J. Divis
|
| | | | 100,000 | | | | | | 18,000 | | |
Michael F. Kanan
|
| | | | 80,000 | | | | | | 18,000 | | |
Philandas Thompson
|
| | | | 100,000 | | | | | | 18,000 | | |
Name and
Principal Position |
| |
Year
|
| |
Base
Salary ($)(1) |
| |
Stock
Awards ($)(2) |
| |
Option
Awards ($)(3) |
| |
Non-Equity
Incentive Plan Compensation ($)(4) |
| |
All
Other Compensation ($)(5) |
| |
Total
Compensation ($) |
| |||||||||||||||||||||
Gregory J. Divis
Chief Executive Officer |
| | | | 2019 | | | | | | 472,292 | | | | | | 33,300 | | | | | | 485,010 | | | | | | 422,344 | | | | | | 23,316 | | | | | | 1,436,262 | | |
| | | 2018 | | | | | | 417,178 | | | | | | — | | | | | | 198,500 | | | | | | 46,750 | | | | | | 23,000 | | | | | | 685,428 | | | ||
| | | 2017 | | | | | | 375,000 | | | | | | 201,375 | | | | | | 505,000 | | | | | | 158,438 | | | | | | 22,800 | | | | | | 1,262,613 | | | ||
Michael F. Kanan
Former Senior Vice President and Chief Financial Officer |
| | | | 2019 | | | | | | 396,718 | | | | | | 33,300 | | | | | | 82,600 | | | | | | 161,861 | | | | | | 453,232(6) | | | | | | 1,127,711 | | |
| | | 2018 | | | | | | 386,100 | | | | | | — | | | | | | — | | | | | | 67,954 | | | | | | 23,000 | | | | | | 477,054 | | | ||
| | | 2017 | | | | | | 357,500 | | | | | | 161,100 | | | | | | 404,000 | | | | | | 120,835 | | | | | | 22,800 | | | | | | 1,066,235 | | | ||
Thomas S. McHugh
Chief Financial Officer |
| | | | 2019 | | | | | | 33,688 | | | | | | — | | | | | | 469,600 | | | | | | — | | | | | | — | | | | | | 503,288 | | |
Jordan S. Dubow
Chief Medical Officer |
| | | | 2019 | | | | | | 293,296 | | | | | | — | | | | | | 273,258 | | | | | | 166,388 | | | | | | 10,282 | | | | | | 743,224 | | |
Phillandas T. Thompson
Senior Vice President and General Counsel |
| | | | 2019 | | | | | | 383,400 | | | | | | 33,300 | | | | | | 103,250 | | | | | | 156,427 | | | | | | 21,780 | | | | | | 698,157 | | |
| | | 2018 | | | | | | 365,968 | | | | | | — | | | | | | — | | | | | | 64,410 | | | | | | 20,000 | | | | | | 450,378 | | | ||
| | | 2017 | | | | | | 326,757 | | | | | | 161,100 | | | | | | 404,000 | | | | | | 110,444 | | | | | | 19,800 | | | | | | 1,022,101 | | | ||
Sandra Hatten
Former Senior Vice President of Quality and Regulatory Affairs |
| | | | 2019 | | | | | | 323,092 | | | | | | 33,300 | | | | | | 82,600 | | | | | | 131,822 | | | | | | 346,306(7) | | | | | | 917,120 | | |
| | | 2018 | | | | | | 314,445 | | | | | | — | | | | | | — | | | | | | 55,342 | | | | | | 11,000 | | | | | | 380,787 | | | ||
| | | 2017 | | | | | | 305,286 | | | | | | 111,875 | | | | | | 303,000 | | | | | | 103,187 | | | | | | 10,800 | | | | | | 834,148 | | |
| | | | | | | | |
Estimated Possible Payouts Under
Non-Equity Incentive Plan Awards(1) |
| |
All Other
Stock Awards: Number of Shares of Stock or Units (#) |
| |
All Other
Option Awards: Number of Securities Underlying Options (#) |
| |
Exercise
or Base Price of Option Awards |
| |
Grant Date
Fair Value of Award ($)(2) |
| |||||||||||||||||||||||||||
Name
|
| |
Grant
Date |
| |
Threshold
($) |
| |
Target
($) |
| |
Maximum
($) |
| ||||||||||||||||||||||||||||||||||||
Gregory J. Divis
|
| | | | | | | | | | — | | | | | $ | 300,000 | | | | | | — | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | 3/7/2019 | | | | | | | | | | | | | | | | | | | | | | | | — | | | | | | 100,000 | | | | | $ | 1.85 | | | | | $ | 103,250 | | |
| | | | | 3/7/2019 | | | | | | | | | | | | | | | | | | | | | | | | 18,000 | | | | | | — | | | | | | — | | | | | $ | 33,300 | | |
| | | | | 5/30/2019 | | | | | | | | | | | | | | | | | | | | | | | | — | | | | | | 400,000 | | | | | $ | 1.71 | | | | | $ | 381,760 | | |
Michael F. Kanan
|
| | | | | | | | | | — | | | | | $ | 158,687 | | | | | | — | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | 3/7/2019 | | | | | | | | | | | | | | | | | | | | | | | | — | | | | | | 80,000 | | | | | $ | 1.85 | | | | | $ | 82,600 | | |
| | | | | 3/7/2019 | | | | | | | | | | | | | | | | | | | | | | | | 18,000 | | | | | | — | | | | | | — | | | | | $ | 33,300 | | |
Thomas S. McHugh
|
| | | | | | | | | | — | | | | | | — | | | | | | — | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | 10/22/2019 | | | | | | | | | | | | | | | | | | | | | | | | — | | | | | | 250,000 | | | | | $ | 3.45 | | | | | $ | 469,600 | | |
Jordan S. Dubow, M.D.
|
| | | | | | | | | | — | | | | | $ | 195,750 | | | | | | — | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | 4/11/2019 | | | | | | | | | | | | | | | | | | | | | | | | — | | | | | | 340,000 | | | | | $ | 1.44 | | | | | $ | 273,258 | | |
Phillandas Thompson
|
| | | | | | | | | | — | | | | | $ | 153,360 | | | | | | — | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | 3/7/2019 | | | | | | | | | | | | | | | | | | | | | | | | — | | | | | | 100,000 | | | | | $ | 1.85 | | | | | $ | 103,250 | | |
| | | | | 3/7/2019 | | | | | | | | | | | | | | | | | | | | | | | | 18,000 | | | | | | — | | | | | | — | | | | | $ | 33,300 | | |
Sandra Hatten
|
| | | | | | | | | | — | | | | | $ | 129,237 | | | | | | — | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | 3/7/2019 | | | | | | | | | | | | | | | | | | | | | | | | — | | | | | | 80,000 | | | | | $ | 1.85 | | | | | $ | 82,600 | | |
| | | | | 3/7/2019 | | | | | | | | | | | | | | | | | | | | | | | | 18,000 | | | | | | — | | | | | | — | | | | | $ | 33,300 | | |
| | | | | | | | |
Option Awards
|
| |
Stock Awards
|
| ||||||||||||||||||||||||||||||
Name
|
| |
Grant Date
|
| |
Number of
Securities Underlying Unexercised Options (#) Exercisable(1) |
| |
Number of
Securities Underlying Unexercised Options (#) Unexercisable(1) |
| |
Option
Exercise Price ($) |
| |
Option
Expiration Date |
| |
Number
of Shares or Units of Stock That Have Not Vested (#)(2) |
| |
Market
Value of Shares or Units of Stock That Have Not Vested ($)(2) |
| |||||||||||||||||||||
Gregory J. Divis
|
| | | | 12/14/2016 | | | | | | 112,500 | | | | | | 37,500(3) | | | | | $ | 10.40 | | | | | | 12/14/2026 | | | | | | — | | | | | | — | | |
| | | | | 12/12/2017 | | | | | | 50,000 | | | | | | 50,000(4) | | | | | $ | 8.95 | | | | | | 12/12/2027 | | | | | | — | | | | | | — | | |
| | | | | 3/22/2018 | | | | | | — | | | | | | 50,000(5) | | | | | $ | 7.06 | | | | | | 3/22/2028 | | | | | | — | | | | | | — | | |
| | | | | 3/7/2019 | | | | | | — | | | | | | 100,000(6) | | | | | $ | 1.85 | | | | | | 3/7/2029 | | | | | | — | | | | | | — | | |
| | | | | 3/7/2019 | | | | | | — | | | | | | — | | | | | $ | — | | | | | | — | | | | | | 18,000(7) | | | | | $ | 135,900 | | |
| | | | | 5/30/2019 | | | | | | — | | | | | | 400,000(8) | | | | | $ | 1.71 | | | | | | 5/30/2029 | | | | | | — | | | | | | — | | |
Michael F. Kanan
|
| | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | |
Thomas S. McHugh
|
| | | | 10/22/2019 | | | | | | — | | | | | | 250,000(9) | | | | | $ | 3.45 | | | | | | 10/22/2029 | | | | | | — | | | | | | — | | |
Jordan S. Dubow, M.D.
|
| | | | 4/11/2019 | | | | | | — | | | | | | 340,000(10) | | | | | $ | 1.44 | | | | | | 4/11/2029 | | | | | | — | | | | | | — | | |
Phillandas T. Thompson
|
| | | | 12/12/2017 | | | | | | 40,000 | | | | | | 40,000(11) | | | | | $ | 8.95 | | | | | | 12/12/2027 | | | | | | — | | | | | | — | | |
| | | | | 3/7/2019 | | | | | | — | | | | | | 100,000(12) | | | | | $ | 1.85 | | | | | | 3/7/2029 | | | | | | 18,000(13) | | | | | $ | 135,900 | | |
Sandra Hatten
|
| | | | 6/26/2015 | | | | | | 100,000 | | | | | | — | | | | | $ | 21.67 | | | | | | 2/29/2020 | | | | | | — | | | | | | — | | |
| | | | | 12/10/2015 | | | | | | 50,000 | | | | | | — | | | | | $ | 14.35 | | | | | | 2/29/2020 | | | | | | — | | | | | | — | | |
| | | | | 12/14/2016 | | | | | | 60,000 | | | | | | — | | | | | $ | 10.40 | | | | | | 2/29/2020 | | | | | | — | | | | | | — | | |
| | | | | 12/12/2017 | | | | | | 30,000 | | | | | | — | | | | | $ | 8.95 | | | | | | 2/29/2020 | | | | | | | | | | | | | | |
| | |
Option Awards
|
| |
Share Awards
|
| ||||||||||||||||||
Name
|
| |
Number of
shares acquired on exercise (#) |
| |
Value
realized on exercise ($) |
| |
Number of
shares acquired on vesting (#) |
| |
Value
realized on vesting ($) |
| ||||||||||||
Gregory J. Divis
|
| | | | — | | | | | | — | | | | | | 15,000 | | | | | | 114,300 | | |
Michael F. Kanan
|
| | | | — | | | | | | — | | | | | | 12,000 | | | | | | 91,440 | | |
Thomas S. McHugh
|
| | | | — | | | | | | — | | | | | | — | | | | | | — | | |
Jordan S. Dubow, M.D.
|
| | | | — | | | | | | — | | | | | | — | | | | | | — | | |
Phillandas T. Thompson
|
| | | | — | | | | | | — | | | | | | 12,000 | | | | | | 91,440 | | |
Sandra Hatten
|
| | | | — | | | | | | — | | | | | | 8,333 | | | | | | 63,497 | | |
Name
|
| |
Cash
Payment ($)(1) |
| |
Value of
Benefits ($)(2) |
| ||||||
Gregory J. Divis
|
| | | $ | 798,000 | | | | | | 33,043 | | |
Michael F. Kanan(3)
|
| | | $ | 408,718 | | | | | | 20,279 | | |
Thomas S. McHugh
|
| | | $ | 385,000 | | | | | | 22,028 | | |
Jordan S. Dubow, M.D.
|
| | | $ | 445,875 | | | | | | — | | |
Phillandas T. Thompson
|
| | | $ | 392.400 | | | | | | 7,099 | | |
Sandra Hatten(4)
|
| | | $ | 323,092 | | | | | | 13,521 | | |
Name
|
| |
Cash
Payment ($)(1) |
| |
Value of
Benefits ($)(2) |
| |
Acceleration
of Equity Awards ($)(3) |
| |||||||||
Gregory J. Divis
|
| | | $ | 798,000 | | | | | | 33,043 | | | | | | 3,116,900 | | |
Thomas S. McHugh
|
| | | $ | 385,000 | | | | | | 22,028 | | | | | | 1,025,000 | | |
Jordan S. Dubow, M.D.
|
| | | $ | 445,875 | | | | | | — | | | | | | 2,077,400 | | |
Phillandas T. Thompson
|
| | | $ | 392.400 | | | | | | 7,099 | | | | | | 751,200 | | |
| | |
Fiscal Year Ended
December 31, |
| |||||||||
| | |
2019
|
| |
2018
|
| ||||||
Audit Fees
|
| | | $ | 1,559,100 | | | | | $ | 1,582,054 | | |
Audit-related Fees
|
| | | | — | | | | | | — | | |
Tax Fees
|
| | | | — | | | | | | — | | |
All Other Fees
|
| | | | — | | | | | | — | | |
Total Fees
|
| | | $ | 1,559,100 | | | | | $ | 1,582,054 | | |
| | |
Share Awards
|
| |||||||||
Name and Position
|
| |
Dollar Value
($)(1) |
| |
Number of
Awards (#) |
| ||||||
Gregory J. Divis, Chief Executive Officer
|
| | | | 1,060,640 | | | | | | 112,000 | | |
Thomas S. McHugh
|
| | | | 378,800 | | | | | | 40,000 | | |
Jordan S. Dubow, M.D.
|
| | | | 378,800 | | | | | | 40,000 | | |
All current executive officers, as a group
|
| | | | 1,818,240(2) | | | | | | 192,000 | | |
All current employees who are not executive officers, as a group
|
| | | | 1,184,697(2) | | | | | | 125,100 | | |
Plan category
|
| |
Number of securities to
be issued upon exercise of outstanding options, warrants and rights |
| |
Weighted-average
exercise price of outstanding options, warrants and rights |
| |
Number of securities
remaining available for future issuance under equity compensation plans (excluding securities reflected in column (a)) |
| |||||||||
| | |
(a)
|
| |
(b)
|
| |
(c)
|
| |||||||||
Equity compensation plans approved by security holders
|
| | | | 5,759,000 | | | | | | 7.84 | | | | | | 565,716 | | |
Equity compensation plans not approved by security holders
|
| | | | — | | | | | | — | | | | | | — | | |
Total
|
| | | | 5,759,000 | | | | | | 7.84 | | | | | | 565,716 | | |